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Protein Coding Gene : Tnfsf15 tumor necrosis factor (ligand) superfamily, member 15
Primary Identifier  MGI:2180140 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  326623
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable death receptor binding activity. Predicted to be involved in positive regulation of cytokine production. Predicted to act upstream of or within positive regulation of canonical NF-kappaB signal transduction. Predicted to be located in plasma membrane. Orthologous to human TNFSF15 (TNF superfamily member 15).
PHENOTYPE: Homozygous targeted mutants display decreased clinical severity in experimental autoimmune encephalomyelitis (EAE) and collagen-induced arthritis. [provided by MGI curators]
  • synonyms:
  • tumor necrosis factor (ligand) superfamily, member 15,
  • VEGI,
  • TL1A,
  • Tnfsf15,
  • TL1
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Features --> Cross References

Genome

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0 Canonical

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0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

Trail: ProteinCodingGene

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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