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Allele : Itpka<tm1Hssh> inositol 1,4,5-trisphosphate 3-kinase A; targeted mutation 1, Hee-Sup Shin

Primary Identifier  MGI:2152168 Allele Type  Targeted
Attribute String  Null/knockout Gene  Itpka
Transmission  Germline Strain of Origin  129S4/SvJae
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin cassette was inserted into the sequence at position 389 from the translation start codon. Northern blot analysis on RNA derived from brain of homozygous mice failed to detect a transcript produced from this allele, and western blot analysis demonstrated that no ITPKA protein is produced in homozygous mice.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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6 Publication categories

Trail: Allele