Primary Identifier | MGI:2152168 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Itpka |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin cassette was inserted into the sequence at position 389 from the translation start codon. Northern blot analysis on RNA derived from brain of homozygous mice failed to detect a transcript produced from this allele, and western blot analysis demonstrated that no ITPKA protein is produced in homozygous mice. |