| Primary Identifier | MGI:2388612 | Allele Type | Targeted |
| Attribute String | Modified regulatory region, Null/knockout | Gene | Tcrg |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Embryonic stem cells carrying a deletion for the HsA enhancer element (Rr282726) were subjected to gene targeting to replace the Ecgamma 1 enhancer element (Rr275254) with a loxP site flanked neomycin resistance gene cassette. Correctly targeted cells, in which the Ecgamma 1 enhancer element was mutated on the same chromosome as the HsA deletion, were transfected with a cre expression plasmid to remove the floxed neo cassette. |
