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Protein Coding Gene : Hspa1l heat shock protein 1-like

Primary Identifier  MGI:96231 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  15482
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable several functions, including ATP hydrolysis activity; ubiquitin protein ligase binding activity; and unfolded protein binding activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in cell body. Part of zona pellucida receptor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and limb segment. Human ortholog(s) of this gene implicated in Kawasaki disease; major depressive disorder; schizophrenia; systemic lupus erythematosus; and uveitis. Orthologous to human HSPA1L (heat shock protein family A (Hsp70) member 1 like).
PHENOTYPE: Mice homozygous for a null allele exhibit normal male fertility. [provided by MGI curators]
  • synonyms:
  • Hspa1l,
  • 70kDa,
  • Msh5,
  • heat shock protein 1-like,
  • MGD-MRK-10942,
  • heat shock protein cognate 70, testis,
  • Hsc70t

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For