Primary Identifier | MGI:2182829 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Tnfrsf21 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Exons 2 and 3, which include the translation initiation site, were replaced with a PGK-neo cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was demonstrated by Northern blot analysis of kidney RNA using a cDNA probe to exon 4. |