Type | disruption phenotype | Description | Mutant mice has normal litter size. At 12 months of age they show significant increase in body weight, which is partly due to fat accumulation in the liver with a subsequent increase in liver mass (PubMed:32092411). They display an abnormal red blood cell morphology, similar to macrocytic anemia characterized by fewer, larger and heterogeneous red cells (PubMed:32092412). |