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Protein Coding Gene : Gna12 guanine nucleotide binding protein, alpha 12

Primary Identifier  MGI:95767 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  14673
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including D5 dopamine receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and protein phosphatase 2A binding activity. Involved in several processes, including regulation of TOR signaling; regulation of fibroblast migration; and regulation of proteasomal ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including Rho protein signal transduction; embryonic digit morphogenesis; and regulation of cell shape. Predicted to be located in lateral plasma membrane; neuron projection; and neuronal cell body. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in brush border membrane and cytoplasm. Is expressed in several structures, including branchial arch; central nervous system; female reproductive system; heart; and retina. Orthologous to human GNA12 (G protein subunit alpha 12).
PHENOTYPE: Mice deficient for this gene do not exhibit any detectable abnormalities. [provided by MGI curators]
  • synonyms:
  • AI504261,
  • expressed sequence AI504261,
  • MGI:2140922,
  • Gna12,
  • expressed sequence AI414047,
  • MGD-MRK-10176,
  • AI414047,
  • MGI:2140857,
  • Galpha12,
  • guanine nucleotide binding protein, alpha 12

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For