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Protein Coding Gene : Epha7 Eph receptor A7

Primary Identifier  MGI:95276 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  13841
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chemorepellent activity; growth factor binding activity; and transmembrane signaling receptor activity. Involved in several processes, including ephrin receptor signaling pathway; negative regulation of nervous system development; and regulation of protein phosphorylation. Acts upstream of or within nephric duct morphogenesis; nervous system development; and positive regulation of neuron apoptotic process. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; foot bone; genitourinary system; and sensory organ. Orthologous to human EPHA7 (EPH receptor A7).
PHENOTYPE: Some homozygous mutants display anencephaly. Mutants also exhibit increased proliferation of neural progenitor cells in the lateral ventricle wall of the adult brain. [provided by MGI curators]
  • synonyms:
  • MDK1,
  • Ebk,
  • Eph receptor A7,
  • embryonic brain receptor tyrosine kinase,
  • Mdk1,
  • Hek11,
  • Epha7,
  • Cek11,
  • Ehk3,
  • MGD-MRK-9291

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For