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Protein Coding Gene : Il36a interleukin 36A
Primary Identifier  MGI:1859324 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  54448
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables cytokine activity. Acts upstream of or within positive regulation of interleukin-6 production and signal transduction. Located in extracellular space. Orthologous to human IL36A (interleukin 36 alpha).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased susceptibility to imiquimod-induced psoriasiform dermatitis but normal susceptibility to dextran sodium sulfate-induced colitis. [provided by MGI curators]
  • synonyms:
  • interleukin 36A,
  • Fil1,
  • interferon 36 alpha,
  • interleukin 1 family, member 6 (epsilon),
  • If36a,
  • IL-1H1,
  • Il36a,
  • Fil1epsilon,
  • Il1f6,
  • interleukin 1 family, member 6
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Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

Trail: ProteinCodingGene

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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