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Protein Coding Gene : Cxcl14 C-X-C motif chemokine ligand 14

Primary Identifier  MGI:1888514 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  57266
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable chemokine activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and killing of cells of another organism. Acts upstream of or within inner ear development; negative regulation of myoblast differentiation; and positive regulation of natural killer cell chemotaxis. Predicted to be located in Golgi apparatus. Is expressed in several structures, including embryo ectoderm; eye; genitourinary system; limb; and vibrissa. Orthologous to human CXCL14 (C-X-C motif chemokine ligand 14).
PHENOTYPE: Homozygous null mutant cause partial lethality before weaning, however surviving null are small but fertile and show insulin-sensitive phenotype in female under high fat diet feeding condition. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI414372,
  • AI414372,
  • MGI:2145226,
  • C-X-C motif chemokine ligand 14,
  • Scyb14,
  • small inducible cytokine subfamily B (Cys-X-Cys), member 14,
  • MGI:1915056,
  • 1200006I23Rik,
  • BRAK,
  • RIKEN cDNA 1110031L23 gene,
  • Kec,
  • 1110031L23Rik,
  • MGI:1915961,
  • RIKEN cDNA 1200006I23 gene,
  • Cxcl14,
  • MIP-2g

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