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Protein Coding Gene : Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C
Primary Identifier  MGI:891969 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  20702
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable identical protein binding activity; protease binding activity; and serine-type endopeptidase inhibitor activity. Acts upstream of or within response to cytokine and response to peptide hormone. Located in extracellular region. Is expressed in gut; liver lobe; and metanephros. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1).
  • synonyms:
  • serine protease inhibitor 1-6,
  • serine (or cysteine) peptidase inhibitor, clade A, member 1C,
  • MGI:891966,
  • Spi1-6,
  • PI3,
  • PI6,
  • serine protease inhibitor 1-3,
  • Serpina1c,
  • Spi1-3
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Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

18 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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