| Primary Identifier | MGI:95690 | Organism | mouse, laboratory |
| Chromosome | 12 | NCBI Gene Number | 238057 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables identical protein binding activity. Involved in positive regulation of gene expression and positive regulation of tendon cell differentiation. Acts upstream of or within several processes, including BMP signaling pathway; morphogenesis of an epithelium; and nervous system development. Located in extracellular region. Is expressed in several structures, including brain; limb; metanephros; and neural tube roof plate. Orthologous to human GDF7 (growth differentiation factor 7). PHENOTYPE: Mice homozygous for a null allele lack D1A neurons in the dorsal spinal cord; some develop severe hydrocephaly with dilated ventricles and late-onset brain defects. Mice homozygous for another null allele show premature death, hydrocephaly, aberrant seminal vesicle development and male sterility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
