Type | MGI:General | Description | homozygotes show a significantly higher dopamine turnover ratio ([3,4-dihydroxyphenylacetic acid (DOPAC) + homovanillic acid (HVA) + 3-methoxytyramine (3-MT)]/dopamine) in the striatum relative to wild-type controls striatal levels of DOPAC, HVA, and 3-MT are increased, whereas dopamine levels remain unchanged |