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Protein Coding Gene : Mepe matrix extracellular phosphoglycoprotein with ASARM motif (bone)

Primary Identifier  MGI:2137384 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  94111
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable extracellular matrix protein binding activity. Acts upstream of or within negative regulation of bone mineralization. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including aorta; bone; connective tissue; lower jaw mesenchyme; and lower leg mesenchyme. Orthologous to human MEPE (matrix extracellular phosphoglycoprotein).
PHENOTYPE: Mice homozygous for disruptions in this gene have increased amounts of trabecular bone in their skeleton and undergo less age related bone loss. Otherwise, they display a normal phenotype. [provided by MGI curators]
  • synonyms:
  • OF45,
  • Mepe,
  • matrix extracellular phosphoglycoprotein with ASARM motif (bone)

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For