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Protein Domain : Matrix extracellular phosphoglycoprotein

Primary Identifier  IPR009837 Type  Family
Short Name  MEPE
description  Matrix extracellular phosphoglycoprotein (also known as Osteoblast/osteocyte factor 45 or osteoregulin) has multiple functions, being involved in cell signalling, mineral homeostasis, and mineralization, as it plays a role in bone mineralization by osteoblasts and cartilage mineralization by chondrocytes [, , ]. It promotes renal phosphate excretion []and inhibits intestinal phosphate absorption [].This entry also includes Ovocleidin-116, the chicken orthologue, which is the major component of the eggshell matrix and is involved in eggshell calcification [].

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0 Parent Features

4 Protein Domain Regions