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Publication : Eki2 is upregulated specifically in the testis during mouse sex determination.

First Author  Hurley TM Year  2004
Journal  Gene Expr Patterns Volume  4
Issue  2 Pages  135-40
PubMed ID  15161093 Mgi Jnum  J:88265
Mgi Id  MGI:3032453 Doi  10.1016/j.modgep.2003.09.010
Citation  Hurley TM, et al. (2004) Eki2 is upregulated specifically in the testis during mouse sex determination. Gene Expr Patterns 4(2):135-40
abstractText  We have identified a gene with gonad restricted expression throughout mouse development, which is orthologous to human EKI2 (ethanolamine kinase 2). Our studies showed that mouse Eki2 expression became upregulated in the male gonad during the period of sex determination. Expression was restricted to the Sertoli cells of the developing testis. Eki2 has sequence similarity to ethanolamine (73%) and choline kinases (54%).
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