| Primary Identifier | MGI:1889576 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 26920 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable dynein complex binding activity. Acts upstream of or within circulatory system development; female germ-line stem cell asymmetric division; and kidney development. Located in meiotic spindle pole; mitotic spindle pole; and perinuclear region of cytoplasm. Is expressed in cerebral cortex ventricular layer; midbrain ventricular layer; and telencephalon ventricular layer. Used to study nephronophthisis. Orthologous to human CNTRL (centriolin). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit cardiac defects, including double outlet right ventricle, atrial septal defects, ventricular septal defects, tricuspid valve stenosis and heart right ventricle hypoplasia, and develop kidney cysts and hydronephrosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
