First Author | Barthelemy I | Year | 1996 |
Journal | Biochem Biophys Res Commun | Volume | 224 |
Issue | 3 | Pages | 870-6 |
PubMed ID | 8713137 | Mgi Jnum | J:34494 |
Mgi Id | MGI:81950 | Doi | 10.1006/bbrc.1996.1114 |
Citation | Barthelemy I, et al. (1996) zhx-1: a novel mouse homeodomain protein containing two zinc-fingers and five homeodomains. Biochem Biophys Res Commun 224(3):870-6 |
abstractText | A cDNA encoding the complete reading frame of a novel homeodomain-containing protein, named zhx-1, has been cloned from a mouse bone marrow stromal cell line. The ORF encodes a protein of 873 amino acids, in which two C2-H2 zinc-fingers and five homeodomains have been identified. These features classify zhx-1 as a member of the ZF class of homeodomain transcription factors, zhx-1 mRNA is widely expressed in adult mouse, although it is preferentially expressed in brain. At least, two homologous mRNAs are present in humans suggesting that zhx-1 is the first member of a novel subclass of homeodomain factors. |