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Protein Coding Gene : Arhgap45 Rho GTPase activating protein 45
Primary Identifier  MGI:1917969 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  70719
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable GTPase activator activity. Predicted to be involved in signal transduction. Predicted to be located in cytosol and plasma membrane. Predicted to be active in membrane. Orthologous to human ARHGAP45 (Rho GTPase activating protein 45).
PHENOTYPE: Homozygous knockout affects naive T and B cell chemotaxis and their entry into lymph nodes and leads to reduced numbers of certain T and B cell sub-populations in blood, LNs and thymus. [provided by MGI curators]
  • synonyms:
  • Arhgap45,
  • MGI:2143851,
  • Rho GTPase activating protein 45,
  • AW539505,
  • 6330406L22Rik,
  • RIKEN cDNA 6330406L22 gene,
  • histocompatibility (minor) HA-1,
  • Hmha1,
  • expressed sequence AW539505
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Genome

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1 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

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Homology

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Interactions

10 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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