| Primary Identifier | MGI:1913948 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 432508 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable exon-exon junction complex binding activity; mRNA binding activity; and ribosomal large subunit binding activity. Predicted to contribute to RNA binding activity. Predicted to be involved in mRNA alternative polyadenylation; positive regulation of RNA export from nucleus; and protein heterotetramerization. Located in nucleus. Is expressed in several structures, including blastocyst; cerebellum; early embryo; retina nuclear layer; and telencephalon. Orthologous to human CPSF6 (cleavage and polyadenylation specific factor 6). PHENOTYPE: Mice heterozygous for a null allele are infertile with no sperm in males. Bone marrow-derived macrophages show lower viral load and increased IFN-beta production after vesicular stomatitis virus infection. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
