| First Author | Fujimori Y | Year | 1998 |
| Journal | Biochem Biophys Res Commun | Volume | 244 |
| Issue | 3 | Pages | 796-800 |
| PubMed ID | 9535745 | Mgi Jnum | J:46796 |
| Mgi Id | MGI:1202090 | Doi | 10.1006/bbrc.1998.8344 |
| Citation | Fujimori Y, et al. (1998) Molecular cloning and characterization of mouse ficolin-A. Biochem Biophys Res Commun 244(3):796-800 |
| abstractText | A novel ficolin-related gene was isolated from the mouse liver lambda ZAPII cDNA library. The protein encoded by this gene consists of both collagen- and fibrinogen-like domains, which are common features of the ficolin family, and was named mouse ficolin-A. The amino acid sequence of mouse ficolin-A is 60.2, 59.8, 59.8, and 59.6% identical to those of porcine ficolin-alpha, -beta, human ficolin-1, and EBP-37/P35, respectively. Northern blot analysis showed that mRNA of mouse ficolin- A is highly expressed in liver and spleen. Immunoblot analysis using an anti-mouse ficolin-A antiserum showed that mouse ficolin-A is a plasma protein with binding activity to elastin and GlcNAc. |
