First Author | Schwaab V | Year | 1995 |
Journal | Gene | Volume | 167 |
Issue | 1-2 | Pages | 25-31 |
PubMed ID | 8566787 | Mgi Jnum | J:30647 |
Mgi Id | MGI:78150 | Doi | 10.1016/0378-1119(95)00551-x |
Citation | Schwaab V, et al. (1995) Cloning of the mouse gene encoding plasma glutathione peroxidase: organization, sequence and chromosomal localization. Gene 167(1-2):25-31 |
abstractText | Using a reverse transcription coupled to PCR amplification strategy, with degenerated primers localized in highly conserved domains of known glutathione peroxidase (GPX) proteins, we have generated, from mouse epididymal RNA, a cDNA fragment which was subsequently used to isolate a genomic clone encoding mouse plasma GPX (GPX3). GPX3 is a major enzyme in reducing lipid hydroperoxides and hydrogen peroxide in plasma. We confirm here that the mouse epididymis is a new site of expression of GPX3 and report, together with the sequence, the structural analysis and the chromosomal localization of the mouse GPX3 single-copy gene to chromosome 11. |