| First Author | Galland F | Year | 1992 |
| Journal | Genomics | Volume | 13 |
| Issue | 2 | Pages | 475-8 |
| PubMed ID | 1319394 | Mgi Jnum | J:919 |
| Mgi Id | MGI:49451 | Doi | 10.1016/0888-7543(92)90277-y |
| Citation | Galland F, et al. (1992) Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene. Genomics 13(2):475-8 |
| abstractText | A new human gene encoding a putative receptor-type tyrosine kinase (RTK) was isolated by screening a placenta cDNA library with a mouse Flt3 probe. The deduced amino acid sequence of the intracellular region of the molecule showed that it was strongly related to the FLT1 and KDR/FLK1 gene products and to a lesser degree to members of the class III RTKs: FMS/CSF1R, PDGFRA/B, KIT, and FLT3. The gene was named FLT4. Cosmid clones of the mouse Flt4 gene were isolated. The human gene was localized to bands q34-q35 of chromosome 5, i.e., slightly telomeric to the CSF1R/PDGRFB tandem of genes, and the mouse homolog to chromosome 11, region A5-B1. |
