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Protein Coding Gene : Ckb creatine kinase, brain

Primary Identifier  MGI:88407 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  12709
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables creatine kinase activity. Involved in futile creatine cycle. Located in myelin sheath. Is active in mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; musculature; and sensory organ. Orthologous to human CKB (creatine kinase B).
PHENOTYPE: Homozygous null mice have abnormal hippocampal morphology with enlarged mossy fiber field size and display resistance to pharmacologically induced seizures, reduced habituation and spatial learning impairments. [provided by MGI curators]
  • synonyms:
  • B-CK,
  • MGD-MRK-1997,
  • creatine kinase, brain,
  • Ck-3,
  • creatine kinase 3,
  • Ckb,
  • MGD-MRK-1990

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For