Primary Identifier | MGI:6199070 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Saa3 |
Strain of Origin | CD-1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Two in-frame nonsense mutations (TAA and TGA) were introduced into exon 1 using an sgRNA and a template oligonucleotide with CRSIPR/Cas9 technology. This mutation creates a p.L14X (p.Leu14Stop) mutation resulting in a severely truncated open reading frame. |