| Primary Identifier | IPR014536 | Type | Family |
| Short Name | Snx9_fam |
| description | Proteins in the sorting nexin 9 subfamily includes SNX9, SNX18 and SNX33 []. They are characterised by the presence of an N-terminal SH3 domain (), a PX domain that is a phosphoinositide-binding module (), and a Bin/Amphiphysin/Rvs (BAR) domain at the C terminus, which allows membrane binding and bending. They are required for progression and completion of mitosis []. This entry also includes the sorting nexin lst-4 from Caenorhabditis elegans. It is involved in the signalling of vulval development by acting as a negative regulator of epidermal growth factor receptor (EGFR) signaling []. |
