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Protein Coding Gene : Agk acylglycerol kinase

Primary Identifier  MGI:1917173 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  69923
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ATP-dependent diacylglycerol kinase activity; acylglycerol kinase activity; and ceramide kinase activity. Acts upstream of or within ceramide biosynthetic process and lipid phosphorylation. Located in membrane. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Sengers syndrome and cataract 38. Orthologous to human AGK (acylglycerol kinase).
PHENOTYPE: T cell specific knockout reduces CD8+ T cell proliferation and antitumor immune responses. [provided by MGI curators]
  • synonyms:
  • acylglycerol kinase,
  • AI465370,
  • MuLK,
  • EST AI465370,
  • Agk,
  • MGI:1889847,
  • multiple substrate lipid kinase,
  • 2610037M15Rik,
  • Mulk,
  • RIKEN cDNA 2610037M15 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For