| Primary Identifier | MGI:106624 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 17925 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables GTPase activator activity and microfilament motor activity. Acts upstream of or within several processes, including Rho protein signal transduction; lamellipodium morphogenesis; and leukocyte chemotaxis. Located in filopodium tip and lamellipodium. Is expressed in several structures, including brain; heart; sensory organ; and skeletal muscle. Human ortholog(s) of this gene implicated in celiac disease. Orthologous to human MYO9B (myosin IXB). PHENOTYPE: Homozygous null mutants breed normal, but shows defect in macrophage motility and chemotaxis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
