| Primary Identifier | IPR045322 | Type | Family |
| Short Name | HECTD1/TRIP12-like |
| description | This entry includes a group of E3 ubiquitin-protein ligases, including HECTD1/TRIP12 from humans, Ufd4 from budding yeasts and UPL3/4 from Arabidopsis. TRIP12 is involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair [, ]. HECTD1 regulates intracellular localization and secretion of Hsp90 and is essential for the correct development of the cranial neural folds and neural tube closure [, ]. |
