| Primary Identifier | IPR038886 | Type | Family |
| Short Name | E3_SLX5/Rfp1 |
| description | The STUbL pathway is alternative pathway for the elimination of sumoylated proteins. STUbLs (SUMO-targeted ubiquitin ligases), as represented by the Rfp1/Slx8 and Rfp2/Slx8 dimers in Schizosaccharomyces pombe, or the Slx5/Slx8 dimer in Saccharomyces cerevisiae, are conserved ubiquitin E3 enzymes that target sumoylated proteins for ubiquitylation and subsequent degradation or recycling [, ]. These complexes function as a two-component Ub ligase that controls genome stability and sumoylation via ubiquitination [, ].This family consists of Rfp1 and Slx5. |
