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Protein Domain : Ino80 subunit 1

Primary Identifier  IPR038014 Type  Family
Short Name  Ies1
description  Ino80 subunit 1 (Ies1) is a component of the INO80 chromatin remodelling complex [].The INO80 complex is involved in transcriptional regulation, DNA replication and probably DNA repair. It remodels chromatin by increasing nucleosome mobility thus allowing access to enzymes that process DNA. Hydrolysis of ATP is required and the INO80 component is an ATPase []. The complex in yeast is composed of at least ARP4, ARP5, ARP8, RVB1, RVB2, TAF14, NHP10, IES1, IES3, IES4, IES6, ACT1, IES2, IES5 and INO80 [, ].

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