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Allele : Prkra<tm1Gcs> protein kinase, interferon inducible double stranded RNA dependent activator; targeted mutation 1, Ganes C Sen

Primary Identifier  MGI:3626341 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prkra
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to replace about 500 bp of sequence encoding the PKR activation domain in exon 8 with a neomycin resistance cassette. No truncated protein was expressed. The mutant hybrid mRNA was shown to contain 1-22 bases of the endogenous sequence, intron 7, 923-934 of the disrupted exon 8 and the entire neo cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Pact<->,
  • Pact<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

9 Publication categories

Trail: Allele