| First Author | Bender K | Year | 1986 |
| Journal | Biochem Genet | Volume | 24 |
| Issue | 1-2 | Pages | 1-11 |
| PubMed ID | 3964226 | Mgi Jnum | J:8260 |
| Mgi Id | MGI:56729 | Doi | 10.1007/BF00502974 |
| Citation | Bender K, et al. (1986) Genetic variation of an acid phosphatase (Acp-2) in the laboratory rat: possible homology with mouse AP-1 and human ACP2. Biochem Genet 24(1-2):1-11 |
| abstractText | A genetic locus controlling the electrophoretic mobility of an acid phosphatase in the rat (Rattus norvegicus) is described. The locus, designed Acp-2, is not expressed in erythrocytes but is expressed in all other tissues studied. The product of Acp-2 hydrolyzes a wide variety of phosphate monoesters and is inhibited by L(+)-tartaric acid. Inbred rat strains have fixed either allele Acp-2a or allele Acp-2b. Codominant expression is observed in the respective F1 hybrids. Backcross progenies revealed the expected 1:1 segregation ratio. Possible loose linkage was found between the Acp-2 and the Pep-3 gene loci at a recombination frequency of 0.36 +/- 0.06. |
