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Publication : Cajal-Retzius cells, Reelin, and the formation of layers.

First Author  Frotscher M Year  1998
Journal  Curr Opin Neurobiol Volume  8
Issue  5 Pages  570-5
PubMed ID  9811621 Mgi Jnum  J:51140
Mgi Id  MGI:1314761 Doi  10.1016/s0959-4388(98)80082-2
Citation  Frotscher M (1998) Cajal-Retzius cells, Reelin, and the formation of layers. Curr Opin Neurobiol 8(5):570-5
abstractText  Early-generated Cajal-Retzius cells in the marginal zone of the cortex synthesize and secrete the glycoprotein Reelin. The reelin gene is deleted in reeler mice, which show characteristic alterations in cortical lamination. Recent studies have shed some light on the role of Cajal-Retzius cells and Reelin in the formation of cell and fiber layers in the neocortex and hippocampus.
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