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Publication : Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene.

First Author  Olsson PG Year  2003
Journal  J Androl Volume  24
Issue  6 Pages  918-20
PubMed ID  14581519 Mgi Jnum  J:86337
Mgi Id  MGI:2679426 Doi  10.1002/j.1939-4640.2003.tb03144.x
Citation  Olsson PG, et al. (2003) Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene. J Androl 24(6):918-20
abstractText  We have cloned and sequenced the entire mouse ldhc gene and mapped it physically in relation to the somatic ldha gene. The 2 genes were found to be oriented in head-to-tail fashion with about a 6-kilobase (kb) distance between the 3' end of ldha and the 5' end of ldhc. The ldhc gene is composed of 43% repetitive elements compared to only 16% in the ldha gene. Despite the close physical distance of mouse ldha and ldhc, the 2 genes have a very different content of repetitive elements, and this most likely reflects different levels of selective pressure.
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