| Primary Identifier | MGI:106212 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 108043 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable acetylcholine binding activity and acetylcholine-gated monoatomic cation-selective channel activity. Predicted to contribute to acetylcholine receptor activity and heterocyclic compound binding activity. Involved in presynaptic modulation of chemical synaptic transmission. Located in presynapse. Is active in dopaminergic synapse. Is expressed in intestine; liver; nervous system; and retina. Human ortholog(s) of this gene implicated in depressive disorder. Orthologous to human CHRNB3 (cholinergic receptor nicotinic beta 3 subunit). PHENOTYPE: Mice homozygous for disruptions in this gene display hyperactivity and reflex abnormalities but were otherwise phenotypically normal. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
