|  Help  |  About  |  Contact Us

Protein Domain : Secreted frizzled-related protein 1

Primary Identifier  IPR026559 Type  Family
Short Name  SFRP1
description  Secreted frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts []. They have a role in regulating cell growth and differentiation in specific cell types.SFRP1 is an antagonist of the Wnt-Frizzled pathway and is involved in regulating many processes, such as vascular cell proliferation [], heart morphogenesis [], bone trabecular formation []and lung morphogenesis [].

0 Child Features

1 Parent Features

1 Protein Domain Regions