Primary Identifier | IPR026559 | Type | Family |
Short Name | SFRP1 |
description | Secreted frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts []. They have a role in regulating cell growth and differentiation in specific cell types.SFRP1 is an antagonist of the Wnt-Frizzled pathway and is involved in regulating many processes, such as vascular cell proliferation [], heart morphogenesis [], bone trabecular formation []and lung morphogenesis []. |