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Protein Domain : Ribonuclease T2, His active site 1

Primary Identifier  IPR018188 Type  Active_site
Short Name  RNase_T2_His_AS_1
description  The fungal ribonucleases T2 from Aspergillus oryzae, M from Aspergillus saitoi and Rh from Rhizopeus niveus are structurally and functionally related 30 Kd glycoproteins []that cleave the 3'-5' internucleotide linkage of RNA via a nucleotide 2',3'-cyclic phosphate intermediates ().Two histidines residues have been shown [, ]to be involved in the catalytic mechanism of RNase T2 and Rh. These residues and the region around them are highly conserved. This entry represents the conserved region containing the first His active site.

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3 Protein Domain Regions