| Primary Identifier | MGI:2444583 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 320712 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables collagen binding activity and heparin binding activity. Involved in negative regulation of cell population proliferation; negative regulation of connective tissue replacement involved in inflammatory response wound healing; and positive regulation of cardiocyte differentiation. Acts upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Located in interstitial matrix. Is expressed in several structures, including connective tissue; embryo mesenchyme; gut; male reproductive gland or organ; and olfactory epithelium. Orthologous to human ABI3BP (ABI family member 3 binding protein). PHENOTYPE: Homozygotes for a null allele show no major changes in anxiety, depression-like behavior, olfactory function or tumor incidence. Homozygotes for a different null allele show reduced cardiac progenitor cell (CPC) differentiation, increased CPC proliferation, and susceptibility to myocardial injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
