Primary Identifier | MGI:3841008 | Allele Type | Chemically induced (ENU) |
Gene | Ifnar2 | Inheritance Mode | Recessive |
Strain of Origin | C57BL/6J | Is Recombinase | false |
Is Wild Type | false | Project Collection | Beutler Mutagenetix |
molecularNote | This mutation was identified in an ex vivo screen of macrophages from G3 progeny of ENU mutagenized male mice for their ability to control viral infection. It comprises an A to T transition in the second of nine exons, which is the first coding exon of the gene, converting the methionine/translation initiation codon at nucleotide position 221 of the cDNA sequence to a codon specifying valine. |