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Allele : Ifnar2<m1Btlr> interferon (alpha and beta) receptor 2; mutation 1, Bruce Beutler

Primary Identifier  MGI:3841008 Allele Type  Chemically induced (ENU)
Gene  Ifnar2 Inheritance Mode  Recessive
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false Project Collection  Beutler Mutagenetix
molecularNote  This mutation was identified in an ex vivo screen of macrophages from G3 progeny of ENU mutagenized male mice for their ability to control viral infection. It comprises an A to T transition in the second of nine exons, which is the first coding exon of the gene, converting the methionine/translation initiation codon at nucleotide position 221 of the cDNA sequence to a codon specifying valine.
  • mutations:
  • Single point mutation
  • synonyms:
  • macro-2,
  • macro-2
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

4 Publication categories

Trail: Allele