Primary Identifier | MGI:2181190 | Allele Type | Targeted |
Attribute String | Conditional ready, Hypomorph, Reporter | Gene | Bmp4 |
Transmission | Germline | Strain of Origin | 129S6/SvEvTac |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This hypomorphic allele is a derivative of Bmp4tm3Blh. LoxP sites were inserted flanking exons 3 and 4, and a promoterless lacZ gene was inserted 3' to the loxP insertions. An frt-flanked neomycin selection cassette that was inserted downstream of the lacZ gene was removed by Flpe mediated recombination in the final allele. |