Primary Identifier | MGI:7517009 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Septin14 |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/cas9-mediated recombination using guide RNAs inserted loxP sites surrounding exons 4 and 5. Cre mediated recombination removed exons 4 and 5. RT-PCR analysis confirmed the absence of mRNA expression in hippocampus and cerebellum tissues from homozygous mice. |