Primary Identifier | MGI:6257738 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Itm2c |
Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NCrl |
Is Recombinase | false | Is Wild Type | false |
Project Collection | IMPC |
molecularNote | This allele produced from project TCPR0313 at TCP by injecting Cas9 mRNA and one guide RNA with the spacer sequence CCTTTCCGGGAGCGGTGGCG. This resulted in a 15-bp deletion from Chr1:85903021 to 85903035_insT (GRCm38) in ENSMUSE00000330277. This mutation is predicted to cause a frameshift with amino acid changes after residue 48 and early truncation 40 amino acids later (p.R48Efs*42). (GRCm38). |