| Primary Identifier | MGI:1860425 | Organism | mouse, laboratory |
| Chromosome | 16 | NCBI Gene Number | 56173 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable structural molecule activity. Predicted to be involved in bicellular tight junction assembly and cell adhesion. Located in bicellular tight junction and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Used to study autosomal recessive nonsyndromic deafness 29. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 29. Orthologous to human CLDN14 (claudin 14). PHENOTYPE: Homozygous mutant mice have a normal endocochlear potential but are deaf due to cochlear hair cell degeneration within the first 3 weeks of age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
