|  Help  |  About  |  Contact Us

Protein Coding Gene : Mas1 MAS1 oncogene

Primary Identifier  MGI:96918 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  17171
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables angiotensin receptor activity and peptide binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway; positive regulation of canonical NF-kappaB signal transduction; and regulation of inflammatory response. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; extraembryonic component; gut; reproductive system; and spleen. Orthologous to human MAS1 (MAS1 proto-oncogene, G protein-coupled receptor).
PHENOTYPE: Mice homozygous for disruptions in this gene show enhanced long term potentiation and higher levels of anxiety. They are otherwise normal and fertile. [provided by MGI curators]
  • synonyms:
  • Mas-1,
  • MGD-MRK-12118,
  • MAS1 oncogene,
  • MGD-MRK-12117,
  • MasR,
  • Mas receptor,
  • Mas1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For