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Allele : Epor<tm2Jni> erythropoietin receptor; targeted mutation 2, James N Ihle

Primary Identifier  MGI:2388346 Allele Type  Targeted
Gene  Epor Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The gene was truncated by replacement of exon 8 sequences encoding the distal half of the cytoplasmic domain with a neomycin resistance cassette. A tyrosine to phenylalanine substitution at residue 343 (Y343F) was also introduced. Expression of the mutant allele was confirmed by RT-PCR analysis of bone marrow RNA from homozygous mutant animals. Sequence analysis of RT-PCR products verified the presence of the Y343F amino acid substitution.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • HM,
  • Epor-HM,
  • EporHM,
  • EporHM,
  • Epor-HM,
  • HM
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

14 Publication categories

Trail: Allele