| Primary Identifier | MGI:1860517 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 54150 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable all-trans-retinol dehydrogenase (NAD+) activity; androstan-3-alpha,17-beta-diol dehydrogenase activity; and androsterone dehydrogenase activity. Predicted to be involved in retinol metabolic process and steroid metabolic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in alimentary system; intestine; liver; metanephros; and stomach. Orthologous to human RDH16 (retinol dehydrogenase 16). PHENOTYPE: Mcie homozygous for a conditional allele activated in enterocytes exhibit reduced NCR+ IL22-producing RORgammat+ innate lymphoid cells and enhanced resistance to colonization by gut pathogens. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
