| Type | MGI:General | Description | in the mutant retina, numerous apoptotic (TUNEL-positive) cells were found in the outer nuclear layer (ONL), and to a much lesser extent in the inner nuclear layer (INL) nitric oxide synthase was induced in microglial cells, which invaded retinal layers and phagocytosed dead cell debris; NOS inhibitors prevented cell death in the INL, but not in the ONL, indicating that loss of INL neurons is mediated by nitric oxide from microglial cells |
