| Primary Identifier | MGI:2443807 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 237542 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable cholesterol binding activity; phosphatidylserine transfer activity; and phospholipid binding activity. Involved in positive regulation of glucose import; positive regulation of insulin receptor signaling pathway; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Acts upstream of or within negative regulation of cell migration and protein localization to nuclear pore. Located in nuclear membrane. Is expressed in several structures, including genitourinary system; heart; immune system; nervous system; and sensory organ. Orthologous to human OSBPL8 (oxysterol binding protein like 8). PHENOTYPE: Mice homozygous for a gene trap allele exhibit elevated of HDL and gender-specific alterations in lipid metabolism. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
