| Type | disruption phenotype | Description | Homozygous knockout mice are normal, reproduce and behave normally. No gross or histological abnormalities in major organs, including the brain are observed (PubMed:11287665). The phosphatidylinositol 4,5- bisphosphate-signaling pathway in cerebral cortex and long-term potentiation are affected (PubMed:11287665). |
